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Rev. Soc. Bras. Med. Trop ; 45(1): 122-124, Jan.-Feb. 2012.
Article in English | LILACS | ID: lil-614922

ABSTRACT

INTRODUCTION: The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening. METHODS: Among the 6,000 newborns referred for investigation of genetic and metabolic diseases, 1,000 were selected for screening for congenital toxoplasmosis by determining the amount of IgM in the eluates of blood collected on filter paper. Positive tests were confirmed using paired serology of the NB and his mother. RESULTS: Out of the 1,000 NBs assessed, one had a positive screening result that was confirmed by paired serology. CONCLUSIONS: The incidence of congenital toxoplasmosis in Belém was 10/10,000 live NBs.


INTRODUÇÃO: O objetivo do estudo foi determinar a incidência da toxoplasmose congênita em um grupo de recém-nascidos (RNs) de Belém, pela triagem neonatal. MÉTODOS: Entre 6.000 RNs, encaminhados para investigação de doenças genéticas e metabólicas, foram selecionados 1.000 para triagem de toxoplasmose congênita, através da pesquisa de anticorpos IgM em eluatos de sangue colhido em papel de filtro. Os testes positivos foram confirmados, através da sorologia pareada do RN e respectiva genitora. RESULTADOS: Dos 1.000 RNs investigados, um apresentou triagem positiva confirmada pela sorologia pareada. CONCLUSÕES: A incidência de toxoplasmose congênita em Belém foi de 10/10.000 RNs vivos.


Subject(s)
Female , Humans , Infant, Newborn , Antibodies, Protozoan/blood , Neonatal Screening , Toxoplasma/immunology , Toxoplasmosis, Congenital/epidemiology , Brazil/epidemiology , Enzyme-Linked Immunosorbent Assay , Incidence , Immunoglobulin G/blood , Immunoglobulin M/blood , Toxoplasmosis, Congenital/diagnosis
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